Periodontal Supplements


Supplements Chosen to Support Periodontal Health Based on Scientific Research

Perio 6 Group

Manufactured by a Triple GMP-Certified Company

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Phyto Daily Multi

Phyto Daily Multi
• Multivitamins can help fill the gaps in one’s diet to help assure people receive the recommended amount of key nutrients needed each day.
• Periodontitis is associated with low serum/plasma micronutrient levels.
• Evidence indicates beneficial outcomes from nutritional interventions for prevention and treatment of periodontitis. (1)
• A review of clinical studies involving multivitamins and/or antioxidants in periodontal disease showed significant improvements in gingival inflammation, bleeding on probing, pocket depths and attachment levels. (2)

Recommendations :
Take one to two tablets daily with food or as directed by your healthcare practitioner.

Two tablets supply:
Ingredients – Amount – Daily Value
Vitamin A (50% as mixed carotenoics and 50% as retinyl acetate) 10,000 IU 200%
Vitamin C (as ascorbic acid and ascorbyl palmitate) 120 mg 200%
Vitamin D3 (as cholecalciferol) 1000 IU 250%
Vitamin E (as d-alpha tocopheryl succinate) 100 IU 333%
Vitamin K (as phytonadione) 120 mcg 150%
Thiamin (as thiamin mononitrate) 25 mg 1667%
Riboflavin 15 mg 882%
Niacin (as niacinamide and niacin) 50 mg 250%
Vitamin B6 (as pyridoxine HCl) 25 mg 1250%
Folate (as calcium L-5-methyltetrahydrofolate) 800 mcg 200%
Vitamin B12 (as methylcobalamin 200 mcg 3333%
Biotin 500 mcg 167%
Pantothenic Acid (as D-calcium pantothenate) 75 mcg 750%
Iodine (as potassium iodide) 150 mcg 100%
Magnesium (as magnesium citrate) 40 mg 10%
Zinc (as zinc citrate) 15 mg 100%
Selenium (as selenium aspartate) 100 mcg 143%
Copper (as copper citrate) 1 mg 50%
Manganese (as manganese citrate) 0.5 mg 25%
Chromium (as chromium polynicotinate) 200 mcg 167%
Molybdenum (as molybdenum aspartate complex) 50 mcg 67%
Choline (as choline bitartrate) 25 mg *
Inositol 25 mg *
Lycopene 6 mg *
Zeaxanthin 2 mg *
Lutein 6 mg *
Resveratrol (from Polygonum cuspidatum root extract) 10 mg *
Proprietary Phytonutrient Blend of:
Citrus Bioflavonoid Complex [standardized to 45% hesperidin], green coffee bean extract [standardized to 45% chlorogenic acid], pomegranate whole fruit extract [standardized to 40% ellagic acid], grape seed extract [standardized to 90% polyphenols], blueberry fruit extract [standardized to 30% total polyphenols and 12% anthocyanins], green tea leaf extract [standardized to 60% catechins and 40% EGCG], bitter melon fruit extract [standardized to 5% bitter principles], prune skin extract [standardized to 50% polyphenols], watercress herb 4:1 extract, Chinese cinnamon (Cinnamomum cassia) bark powder, Indian gum Arabic tree bark and heartwood extract [standardized to 6% catechins], rosemary extract [standardized to 11% min phenolic diterpenes and 7.6 % min sum of carnosol+carnosic acid], artichoke leaf extract [standardized to 0.3% cynarins and 1% chlorogenic acid].

Other Ingredients :
Microcrystalline cellulose, cellulose, croscarmellose sodium, silica, stearic acid (vegetable), coating (water, hypromellose, medium chain triglycerides, hydroxypropylcellulose, and sodium copper chlorophyllin).

Do not use is pregnant or nursing. Excess vitamin A may be toxic and may increase the risk of birth defects. Pregnant women and women who may become pregnant should not exceed 5000 IU of preformed vitamin A (retinyl acetate) per day,
If you are taking medication consult your healthcare practitioner before use. Keep out of the reach of children.

Gluten Free.

1. Van der Velden U, Kuznanova D, Chapple I L S. Micronutritional approaches to periodontal therapy.  J Clin Periodotal 2011 Mar; 38 Suppl 1A: 142-158.
2. Munoz C, Stephens J, Kim J, et al. Effect of a nutritional supplement on periodontal status. Compendium of Continuing Education in Dentistry 2011 Mar; 38 Suppl A: 142-158.

Optimal Cal/Mag

Optimal CalMag


• Vitamin D and calcium are involved in bone and teeth formation, growth and repair.
• Phosphorous is utilized for growth and repair of body cells and tissues.
• Magnesium is involved in a wide range of functions in human physiology.
• The primary function of phosphorus is in the formation of bones and teeth.
• Deficiencies of Vitamin D or calcium may lead to resorption of bone around the teeth and destruction of the periodontal ligaments that anchor the teeth to the jawbone. (1)
• Clinical trials have demonstrated that magnesium deficiency is associated with periodontal disease, and patients taking magnesium supplements showed improved periodontal health, including reduced probing depth, less attachment loss and less tooth loss. (2)

Recommendations :
Take three tablets once daily or as directed by your healthcare professional.

Three tablets supply:
Ingredients – Amount – Daily Value
Vitamin D (as cholecalciferol) 600 IU 150%
Calcium (as MCHC and dicalcium phosphate) 600 mg 60%
Phosphorus (as MCHC and dicalcium phosphate) 378 mg 38%
Magnesium (as magnesium citrate, magnesium aspartate, and magnesium bis-glycinate) 300 mg 75%
Microcrystalline Hydroxyapatite Concentrate (MCHC) 1500 mg *
Other Ingredients :
Microcrystalline cellulose, croscarmellose sodium, sodium starch glycolate, cellulose, stearic acid (vegetable), silica, and coating (deionized water, microcrystalline cellulose, polyethylene glycol, and carrageenan)

If you are pregnant or nursing consult your healthcare practitioner before use.

1. Jeffcoat MK, Chesnut CH. Systemic osteoporosis and oral bone loss: evidence shows increased risk factors.
J Am Dental Assoc 1993 Nov; 45-56.
2. Meissel P, Schwahn C, Luedemann J, et al. Magnesium deficiency is associated with periodontal disease. J Dent Res 2005 Oct; 84 (10): 937-941.

Optimal D3 1000
Optimal D3 5000

Optimal D3 2000

• Vitamin D3 deficiency is implicated in a variety of diseases, including periodontitis.
• Vitamin D3 is essential for calcium absorption and helps maintain the proper balance of calcium and phosphorus in bones.
• Vitamin D3 plays a role in calcium and bone metabolism. Vitamin D3 has been shown to function in cancer prevention, immunity and cardiovascular regulation, and plays a role in maintaining oral health through its effects on bone and mineral metabolism and innate immunity. (1)
• Deficiencies of Vitamin D3 may lead to the resorption of bone around the teeth and destruction of the periodontal ligaments that anchor the teeth to the jawbone. (2)

One tablet daily with food, or as directed by your healthcare practitioner.

One tablet supplies:
Vitamin D3 (as cholecalciferol)………………………..1,000 or 5000 IU
Other Ingredients:
Microcrystalline cellulose, sodium starch glycolate, stearic acid, and silica.

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

1. Amano Y, Komiyama K and Makishima M. Vitamin D and periodontal disease. J Oral Sci 2009 Mar; 51 (1): 11-20.
2. Jeffcoat MK, Chesnut CH. Systemic osteoporosis and oral bone loss: evidence shows increased risk factors. J Am Dental Assoc 1993 Nov; 45-56.

Omega Pro 500

Omega Pro 500

• Omega-3 fatty acids modulate cellular function in numerous processes, including brain and visual development, inflammatory reactions, thrombosis and carcinogenesis. (1)
• Omega-3 fatty acids have also been shown to have therapeutic anti-inflammatory and protective actions in inflammatory diseases, including periodontitis. (1)
• Results of a double blind study comparing docosahexanoic acid (DHA) plus eicosopentanoic acid (EPA) vs placebo in patients with chronic periodontitis found significant reductions in probing depths and significant attachment gains after 3 and 6 months in the DHA and EPA group. (2)
• Another clinical trial demonstrated that patients treated with omega-3 fatty acids had significantly less periodontal disease progression over five years then the reference group. (3)

Take two softgels up to three times daily with food or as directed by your healthcare practitioner.

Two softgels supply:
Calories from Fat…………………..18
Total Fat……………………………1 g
Cholesterol……………………….< 5 mg
Natural Marine Lipid Concentrate….2 g
EPA (Eicosapentaenoic acid)…….600 mg
DHA (Docosahexaenoic acid)……400 mg

Other Ingredients:
Gelatin, purified water, glycerin, natural lemon flavor, mixed tocopherols, rosemary, and ascorbyl palmitate. Contains: fish (herring, sardine, anchovy).
* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

1. Surette M. The science behind dietary omego-3 fatty acids. CMAJ 2008 Jan 15; 178 (2): 177-180.
2. El-Sharkawy H, Aboelsaad N, Eliwa M, et al. Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 fatty acids and low-dose aspirin.
J Periodontal 2010 November; 81 (11): 1635-1643.
3. Iwasaki M, Yoshihara A, Moynihan P, et al. Longitudinal relationship between dietary omega-3 fatty acids and periodontal disease. Nutrition 2010 Nov-Dec; 26 (11-12): 1105-1109.

CoQ-10 (100 mg)

CoQ 10

• CoQ-10 is an important vitamin-like substance required for the proper function of many organs and chemical reactions in the body, and helps provide energy to cells.
• Patients with periodontal disease commonly have a deficiency in CoQ-10 in gingival tissue. (1)
• In a double blind clinical trial, patients treated with CoQ-10 had a significant reduction in the symptoms of periodontal disease after three weeks of treatment. (2)

SUGGESTED USE: 1 or more soft gel capsules per day or as recommended by your health care professional.
Contraindications – If you are pregnant or nursing, consult your physician before taking this product. This product contains the following potential allergen: soy. Those taking blood thinning medications should use caution.

These statements have not been evaluated by the FDA. This product is not intended to treat, diagnose, prevent, or cure any disease. Consult a physician before taking. Should you experience any serious physical side effects from taking these nutritional supplements, discontinue and call your doctor immediately.

1. Nakamura R, Littarru G and Folkers K. Deficiency of coenzyme Q in gingiva of patients with periodontal disease. Int J Vitam Nutr Res 1973; 43:84-92
2. Wilkinson EG, Arnold RM and Folkers K. Adjunctive treatment of periodontal disease with coenzyme Q10. Res Commun Chem Pathol Pharmacol 1976; 14 (4): 715-719.
3. Iwasaka M, Manz MC, Taylor GW, et al. Relations of serum ascorbic acid and alpha-tocopherol to periodontal; disease. J Dent Res 2012 Feb; 91 (2): 167-172.

Pro Flora Balance

Pro Flora Balance

• Probiotics are broadly categorized in two genus, Lactobaccilus and Bifidobacterium, and are associated with periodontal health status. These probiotics are able to affect gingivitis and plaque composition positively. (1)
• A significant decrease in gingival bleeding and a reduction in gingivitis were observed after a two week intake of probiotic species. (2)
• In a double blind study, probiotics decreased the plaque index and pocket probing depth significantly in patients who were smokers; and also reduced the prevalence of periodontal pathogens. (3)
• Another study found normalization of micro flora and reduction of signs of gingivitis and periodontitis. (4)

1. Gupta V, Gupta B. probiotics and periodontal disease: a current update. J Oral health Comm Dent 2010; 4 (Spl): 35-37.
2. Krasse P, Carlsson B, dahl C, et al. A decreased gum bleeding and reduced gingivitis by the probiotic Lactobacillus reutei. Swed Dent J 2006; 30: 55-60.
3. Shimauchi H, mayanagi G, Nakaya S. Improvement of periodontal condition by probiotics with lactobacillis salivarius WB21: a randomized double blind, placebo
controlled study. J Clin Periodontal 2008; 35: 897-905.
4. Grudianov AI, Dimitrieva NA, Fomenka EV. Use of probiotics Bifidumbacterium and Acilact in tablets in therapy of periodontal inflammation.


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